Sasaki invested a lot in her turnips in animal crossing, spending 2m for them, but she waited a bit too long and found the price of it was halved. She waited a bit longer, and the price dropped again, and waited some more just before they went bad and the price had dropped again. Truly, her luck is abysmal.
That said, apparently fellow Nijisanji VTuber Belmond Banderas managed to help her, don't really know how as I'm not familiar with the game mechanics of Animal Crossing, but apparently saved her from the massive loss of money.