No, I think she's just one of those people who you absolutely, positively cannot leave anywhere near the shiny red buttons.
Obviously, you should handle Mao using the Overlord's Checklist mentality - the big shiny red button that says "Self Destruct" will instead cause a jet of water to spray whoever pushes the button. If it is somehow necessary to have a self destruct button, it will instead be a plain button labeled "sewage ventilation".
Rampaging Bear PoseFeels like this is no laughing matter, doesn't it...What have you done!?
You utter buffoon!It was nothing, really.Okay, Mao-chan, let's... go...?MAO-CHAAAN!Mao-chan...Even guiding us around!Thank you, Oniguma-san!That's the Mountain Witch's house over there.We're here!