Logahn said: It's not a friggin' transsexual, she maybe was long ago in japaneze version, however Capcom officially admits Poison as a full 100% woman now >.<
In USA she's a transgender, in Japan she's just a man Seth Killian confirmed it yo
^Ono said it's up to personal interpretation, the transexual/hermaphrodite story is not "canon" in any way. Back in the day there were problems with beating the shit out of women, so they said that as a quick and easy solution. Poison was made with every intention of being a woman right from the get go.